Chapter 7: Bitumen occurrences

7 Chapter 7 : Measles

I. Disease Description Measles is an acute viral illness caused by a virus in the family paramyxovirus, genus Morbillivirus. Measles is characterized by a prodrome of fever (as high as 105°F) and malaise, cough, coryza, and conjunctivitis, followed by a maculopapular rash.1 The rash spreads from head to trunk to lower extremities. Measles is usually a mild or moderately severe illness. However,...

Chapter 7 Taxonomy Design

This chapter discusses the design of taxonomies to be used in dynamic taxonomy systems. Although the only actual requirement of dynamic taxonomies is a multidimensional classification, i.e., objects are classified under more than one concept, an organization by facets is normally used. In the first section, we provide guidelines for the design of DT taxonomies, which include the automatic const...

Chapter 7: Pharmacogenomics

There is great variation in drug-response phenotypes, and a "one size fits all" paradigm for drug delivery is flawed. Pharmacogenomics is the study of how human genetic information impacts drug response, and it aims to improve efficacy and reduced side effects. In this article, we provide an overview of pharmacogenetics, including pharmacokinetics (PK), pharmacodynamics (PD), gene and pathway i...

Chapter 7 . Covariate Selection

This chapter addresses strategies for selecting variables for adjustment in nonexperimental comparative effectiveness research (CER), and uses causal graphs to illustrate the causal network relating treatment to outcome. While selection approaches should be based on an understanding of the causal network representing the common cause pathways between treatment and outcome, the true causal netwo...

CHAPTER 7 Stella